2 November 2023

Bidirectional movement of tunicamycin in Arabidopsis thaliana

Anh H. Ngo, Yu-Ching Wu, Yuki Nakamura - New Phytologist, 2023

Abstract

Various environmental factors are linked to endoplasmic reticulum (ER) stress, which is caused by an accumulation of misfolded proteins in the ER and membrane lipid disturbance (Xu & Taubert, 2021). The cellular response to ER stress, termed the ER stress response, including the unfolded protein response (UPR), has been extensively studied in a number of model organisms including higher plants (Yu et al., 2021). Plants as a model organism for ER stress allow for investigating organ-specific, tissue-specific, and cell type-specific ER stress responses. In addition, an emerging issue of the systemic ER stress responses in a whole living organism may be investigated, which significantly advances our current understanding of the cell biology of ER stress response (Cho & Kanehara, 2017; Lai et al., 2018).

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