Legume crops are essential for both human nutrition and the sustainability of agricultural production systems. However, realizing their full nutritional and environmental potential requires overcoming key challenges that constrain their cultivation and consumption.
Our research is primarily applied, integrating molecular genetics, genomics, and high-throughput analytical approaches to identify and characterise genetic loci that can be leveraged to enhance the resilience and quality of legume crops.
Understanding molecular and genetic mechanisms of drought tolerance
Legume species such as cowpea are often cultivated on marginal lands that receive less than 300 mm of annual rainfall, making drought a major constraint in key production regions, particularly across sub-Saharan Africa. Although several cowpea accessions with enhanced drought tolerance have been identified, the underlying molecular and genetic mechanisms remain poorly understood.
In our laboratory, we aim to elucidate the key mechanisms underlying drought tolerance in cowpea by integrating physiological characterisation with gene expression analyses to explore the transcriptional regulators and signalling pathways that govern drought-adaptive traits. Our ultimate goal is to identify candidate genes and quantitative trait loci (QTLs) that can be leveraged in breeding programmes to develop cowpea varieties with improved drought resilience.
Enhancing nutritional and end-use quality of legumes
Many legumes contain secondary metabolites that act as antinutritional factors, reducing nutrient bioavailability (e.g. phytic acid and phenolic compounds), affecting consumer acceptance (e.g. raffinose family oligosaccharides, saponins, and volatile compounds), or limiting processing efficiency (e.g. hard-to-cook and hard-seed coat traits).
We have established and optimised high-throughput assays to quantify these traits and facilitate the identification of genetic loci that can be used in precision breeding programmes aimed at developing legume varieties with improved nutritional profiles, sensory qualities, and processing characteristics.
I completed my PhD at the University of Reading in Professor Donal O’Sullivan’s lab, where I worked on characterising faba bean seed protein composition and mapping its underlying genetics. I then joined John Innes Centre in Norwich as a postdoctoral researcher to work on the genetics of pea nutritional quality in the labs of Professor Janneke Balk and Professor Claire Domoney. My current research at Crop Science Centre aims to enhance the nutritional and culinary quality of legumes and other underutilised food crops by discovering the underlying genetic mechanisms.
Publication
Identification of significant genome-wide associations and QTL underlying variation in seed protein composition in pea (Pisum sativum, L.).
Date: 8 July 2024
Contributors: Warsame, A. O., Balk, J., & Domoney, C
Journal: bioRxiv
Publication
Genetic analysis of global faba bean diversity, agronomic traits and selection signatures
Date: 19 April 2023
Contributors: Cathrine Kiel Skovbjerg, Deepti Angra, Tom Robertson‑Shersby‑Harvie, Jonathan Kreplak, Gabriel Keeble‑Gagnère, Sukhjiwan Kaur, Wolfgang Ecke, Alex Windhorst, Linda Kærgaard Nielsen, Andrea Schiemann, Jens Knudsen, Natalia Gutierrez, Vasiliki Tagkouli, Lavinia Ioana Fechete, Luc Janss, ·Jens Stougaard, Ahmed Warsame, Sheila Alves, Hamid Khazaei, Wolfgang Link, Ana Maria Torres, Donal Martin O’Sullivan, Stig Uggerhøj Andersen
Journal: Theoretical and Applied Genetics
Publication
The giant diploid faba genome unlocks variation in a global protein crop.
Date: 8 March 2023
Contributors: Murukarthick Jayakodi, Agnieszka A. Golicz, Jonathan Kreplak, Lavinia I. Fechete, Deepti Angra, Petr Bednář, Elesandro Bornhofen, Hailin Zhang, Raphaël Boussageon, Sukhjiwan Kaur, Kwok Cheung, Jana Čížková, Heidrun Gundlach, Asis Hallab, Baptiste Imbert, Gabriel Keeble-Gagnère, Andrea Koblížková, Lucie Kobrlová, Petra Krejčí, Troels W. Mouritzen, Pavel Neumann, Marcin Nadzieja, Linda Kærgaard Nielsen, Petr Novák, Jihad Orabi, Sudharsan Padmarasu, Tom Robertson-Shersby-Harvie, Laura Ávila Robledillo, Andrea Schiemann, Jaakko Tanskanen, Petri Törönen, Ahmed O. Warsame, Alexander H. J. Wittenberg, Axel Himmelbach, Grégoire Aubert, Pierre-Emmanuel Courty, Jaroslav Doležel, Liisa U. Holm, Luc L. Janss, Hamid Khazaei, Jiří Macas, Martin Mascher, Petr Smýkal, Rod J. Snowdon, Nils Stein, Frederick L. Stoddard, Jens Stougaard, Nadim Tayeh, Ana M. Torres, Björn Usadel, Ingo Schubert, Donal Martin O’Sullivan, Alan H. Schulman & Stig Uggerhøj Andersen
Journal: Nature
Publication
Seed Development and Protein Accumulation Patterns in Faba Bean (Vicia faba, L.)
Date: 18 July 2022
Contributors: Cathrine Kiel Skovbjerg, Deepti Angra, Tom Robertson‑Shersby‑Harvie, Jonathan Kreplak, Gabriel Keeble‑Gagnère, Sukhjiwan Kaur, Wolfgang Ecke, Alex Windhorst, Linda Kærgaard Nielsen, Andrea Schiemann, Jens Knudsen, Natalia Gutierrez, Vasiliki Tagkouli, Lavinia Ioana Fechete, Luc Janss, Jens Stougaard, Ahmed Warsame, Sheila Alves, Hamid Khazaei, Wolfgang Link, Ana Maria Torres, Donal Martin O’Sullivan, Stig Uggerhøj Andersen
Journal: Journal of Agricultural and Food Chemistry
Publication
Identification and Quantification of Major Faba Bean Seed Proteins
Date: 17 July 2020
Contributors: Ahmed O. Warsame, Nicholas Michael, Donal M. O’Sullivan, Paola Tosi
Journal: Journal of Agricultural and Food Chemistry
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