Crop Science Centre

Driven by impact, fuelled by excellence

Alexis L Sperling

Alexis L Sperling

Research Associate
Plant-parasitic interactions

alb84 [at] cam.ac.uk
Biography

I started off at the University of Victoria (Canada) in biochemistry and biology and then moved to KTH (Sweden) for my masters in bioreactors and protein engineering. I did my PhD at the University of Cambridge (UK) in the Zoology Department on epithelial patterning in Drosophila eggs. My first postdoc was on centrosome migration in Drosophilaeggs and my second postdoc was on the genetic basis of parthenogenesis in Drosophila. I am excited to take my knowledge in cell and developmental biology into my new research on the cellular and molecular biology of plant parasite interactions, specifically on effector biogenesis in nematodes. I am working towards building knowledge of the fundamental biology of pathogenic nematodes in order to gain insight into how we can prevent pathogenic nematode infections. 

 

Publications

Alexis L. Sperling, Daniel K. Fabian, Erik K. Garrison, and David M. Glover. (2023) A genetic basis for facultative parthenogenesis in Drosophila. Current Biology (accepted)

Alexis L. Sperling and David M. Glover. (2023) Parthenogenesis in dipterans: a genetic perspective.  Royal Society B: Biological Sciences. 290: 20230261

Alexis L. Braun, Francesco Meghini, Gema Villa-Fombuena, Morgane Guermont, Elisa M. Fernandez, Zhang Qian, Maria D. Martin-Bermudo, Acaimo Gonzalez-Reyes, David M. Glover, Yuu Kimata. (2021) The careful control of Polo kinase by APC/C-Ube2C ensures the intercellular transport of germline centrosomes during Drosophila oogenesis. Open Biology. DOI: 10.1098/rsob.200371

Malmberg J, Perols A, Varasteh Z, Altai M, Braun A, Sandström M, Garske U, Tolmachev V, Orlova A,  Eriksson-Karlström A (2011) Comparative evaluation of synthetic anti-HER2 Affibody molecules site-specifically labelled with 111In using N-terminal DOTA, NOTA and NODAGA chelators in mice bearing prostate cancer xenografts. European Journal of Nuclear Medicine Molecular Imaging. DOI: 10.1007/s00259-011-1992-9.