Lida Derevnina
Head of Crop Pathogen Immunity Group
Research group: Crop pathogen immunity
Biography
My research aims to improve our understanding of how pathogens invade plants to cause disease, and how plants perceive and respond to these invading pathogens. My current work focuses on mechanistic investigations of plant NLR immune networks and pathogen effector functions. My ultimate goal is to develop crops with long-lasting resistance to multiple pathogens, alleviating the challenges caused by biotic threats in global food production.
Publications
Publication
The origin, deployment, and evolution of a plant-parasitic nematode effectorome
Date: 5 January 2024
Contributors: Beth Molloy, Dio S. Shin, Jonathan Long, Clement Pellegrin, Beatrice Senatori, Paulo Vieira, Peter Thorpe, Anika Damm, Mariam Ahmad, Kerry Vermeulen, Lida Derevnina, Siyuan Wei, Alexis Sperling, Estefany Reyes Estévez, Samuel Bruty, Victor Hugo Moura de Souza, Olaf Prosper Kranse, Tom Maier, Thomas Baum, Sebastian Eves-van den Akker
Journal: Biorxiv
Publication
The battle within: How pathogen effectors suppress NLR-mediated immunity
Date: 7 August 2023
Contributors: Chih-hang Wu, Lida Derevnina
Journal: Current Opinion in Plant Biology
Publication
Resurrection of plant disease resistance proteins via helper NLR bioengineering
Date: 3 May 2023
Contributors: Mauricio P Contreras, Hsuan Pai, Muniyandi Selvaraj, AmirAli Toghani, David M Lawson, Yasin Tumtas, Cian Duggan, Enoch Lok Him Yuen, Clare E M Stevenson, Adeline Harant, Abbas Maqbool, Chih-Hang Wu, Tolga O Bozkurt, Sophien Kamoun, Lida Derevnina
Journal: Science Advances
Publication
Sensor NLR immune proteins activate oligomerization of their NRC helpers in response to plant pathogens
Date: 1 March 2023
Contributors: Mauricio P Contreras, Hsuan Pai, Yasin Tumtas, Cian Duggan, Enoch Lok Him Yuen, Angel Vergara Cruces, Jiorgos Kourelis, Hee-Kyung Ahn, Kim-Teng Lee, Chih-Hang Wu, Tolga O Bozkurt, Lida Derevnina, Sophien Kamoun
Journal: The EMBO Journal
Publication
Plant pathogens convergently evolved to counteract redundant nodes of an NLR immune receptor network.
Date: 23 August 2021
Contributors: Derevnina L, Contreras MP, Adachi H, Upson J, Vergara Cruces A, Xie R, Skłenar J, Menke FLH, Mugford ST, MacLean D, Ma W, Hogenhout S, Goverse A, Maqbool A, Wu CH, Kamoun S
Journal: PLOS Biology
Publication
Intra-strain Elicitation and Suppression of Plant Immunity by Ralstonia solanacearum Type-III Effectors in Nicotiana benthamiana.
Date: 13 July 2020
Contributors: Sang Y, Yu W, Zhuang H, Wei Y, Derevnina L, Yu G, Luo J, Macho AP
Journal: Plant Communications
Publication
An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species.
Date: 27 November 2019
Contributors: Adachi H, Contreras MP, Harant A, Wu CH, Derevnina L, Sakai T, Duggan C, Moratto E, Bozkurt TO, Maqbool A, Win J, Kamoun S.Elife
Journal: eLife
