Crop Science Centre

Driven by impact, fuelled by excellence

Mandana Miri

Mandana Miri

Impact manager
Research support

Biography

Mandana received her Ph.D. in Cell and Molecular Biology at the University of Western, Canada under supervision of Professor Krzysztof Szczyglowski where she investigated the crosstalk between two plant hormones, cytokinin and ethylene, in the context of nodule and infection thread formation in the model legume Lotus japonicus. Her work led to several publications, awards, grants, accolades, and scholarships including the “Best Thesis Award”. In 2018, She moved to Sainsbury Laboratory Cambridge University to purse a Postdoctoral Research position with Professor Giles Oldroyd working on engineering nitrogen-fixing cereals. In 2019, she was awarded Natural Sciences & Engineering Research Council of Canada (NSERC) Postdoctoral Fellowship to continue with her postdoctoral research at the University of Cambridge. Having always been passionate about impact-driven science, she joined Crop Science Centre to work on driving impact and outcomes in product development from the research outputs from Engineering the Nitrogen Symbiosis for Africa (ENSA) project.

Publications

 Inside out: root cortex-localized LHK1 cytokinin receptor limits epidermal infection of Lotus japonicus roots by Mesorhizobium loti.

Miri M, Janakirama P, Huebert T, Ross L, McDowell T, Orosz K, Markmann K, Szczyglowski K.New Phytol. 2019 May;222(3):1523-1537. doi: 10.1111/nph.15683. Epub 2019 Feb 14.PMID: 30636324 Free article.

 Lotus japonicus NF-YA1 Plays an Essential Role During Nodule Differentiation and Targets Members of the SHI/STY Gene Family.

Hossain MS, Shrestha A, Zhong S, Miri M, Austin RS, Sato S, Ross L, Huebert T, Tromas A, Torres-Jerez I, Tang Y, Udvardi M, Murray JD, Szczyglowski K.Mol Plant Microbe Interact. 2016 Dec;29(12):950-964. doi: 10.1094/MPMI-10-16-0206-R. Epub 2017 Jan 3.PMID: 27929718 Free article.

 Into the Root: How Cytokinin Controls Rhizobial Infection.

Miri M, Janakirama P, Held M, Ross L, Szczyglowski K.Trends Plant Sci. 2016 Mar;21(3):178-186. doi: 10.1016/j.tplants.2015.09.003. Epub 2015 Oct 14.PMID: 26459665 Review.

 Lotus japonicus cytokinin receptors work partially redundantly to mediate nodule formation.

Held M, Hou H, Miri M, Huynh C, Ross L, Hossain MS, Sato S, Tabata S, Perry J, Wang TL, Szczyglowski K.Plant Cell. 2014 Feb;26(2):678-94. doi: 10.1105/tpc.113.119362. Epub 2014 Feb 28.PMID: 24585837 Free PMC article.

 Expression and Single-step Purification of GRA8 Antigen of Toxoplasma gondii in Escherichia coli.

Babaie J, Miri M, Sadeghiani G, Zare M, Khalili G, Golkar M.Avicenna J Med Biotechnol. 2011 Apr;3(2):67-77.PMID: 23407862 Free PMC article.

 Site-directed mutagenesis enhances the activity of NADH-FMN oxidoreductase (DszD) activity of Rhodococcus erythropolis.

Kamali N, Tavallaie M, Bambai B, Karkhane AA, Miri M.Biotechnol Lett. 2010 Jul;32(7):921-7. doi: 10.1007/s10529-010-0254-4. Epub 2010 Mar 28.PMID: 20349330

 Production of a recombinant alkane hydroxylase (AlkB2) from Alcanivorax borkumensis.

Miri M, Bambai B, Tabandeh F, Sadeghizadeh M, Kamali N.Biotechnol Lett. 2010 Apr;32(4):497-502. doi: 10.1007/s10529-009-0177-0. Epub 2009 Dec 2.PMID: 19953301