Crop Science Centre

Driven by impact, fuelled by excellence

Professor Giles E. D. Oldroyd

Professor Giles E. D. Oldroyd
FRS

Crop Science Centre Director and Russell R Geiger Professor of Crop Science
Sustainable crop nutrition

Biography

Giles Oldroyd studies interactions between plants and beneficial micro-organisms, both bacteria and fungi, that aid in the uptake of nutrients from the environment, especially nitrogen and phosphorus. These microbial associations are intracellular, allowing tight control of nutrient exchange, with sources of carbon delivered to the microorganisms from the plant in exchange for nitrogen and phosphorus. Giles’ work has dissected the signal transduction pathway in plants that allows the recognition of beneficial microorganisms and the mechanisms by which plant development is modified to support these interactions.

Giles received his BA in Plant Biology in 1994 from the University of East Anglia and his PhD in 1998 from the University of California, Berkeley. He began work in symbiotic associations in plants as a Howard Hughes Medical Institute postdoctoral fellow at Stanford University, California, under the guidance of Professor Sharon Long. He started his independent research career in 2002 as a BBSRC David Philips Fellow at the John Innes Centre in Norwich. He joined SLCU as a group leader in November 2017 (https://www.slcu.cam.ac.uk/people/giles-oldroyd), and became the Russell R Geiger Professor of Crop Sciences and the director of the Crop Science Centre in October 2019. Giles has been honoured with the Society of Experimental Biology President’s Medal, a Royal Society Wolfson Research merit award, the EMBO Young Investigator award and now leads an international programme focused on engineering nitrogen-fixing cereals funded by the Bill and Melinda Gates Foundation.

Publications

A mycorrhiza-associated receptor-like kinase with an ancient origin in the green lineage
Héctor Montero, Tak Lee, Boas Pucker, Gabriel Ferreras-Garrucho, Giles Oldroyd, Samuel F Brockington, Akio Miyao, Uta Paszkowski Proceedings of the National Academy of Sciences of the United States of America 2021-06-23 pmid:34161289 pmc:PMC8237591 doi:10.1073/pnas.2105281118

Lipid exchanges drove the evolution of mutualism during plant terrestrialization
Mélanie K Rich, Nicolas Vigneron, Cyril Libourel, Jean Keller, Li Xue, Mohsen Hajheidari, Guru V Radhakrishnan, Aurélie Le Ru, Seydina Issa Diop, Giacomo Potente, Elena Conti, Danny Duijsings, Aurélie Batut, Pauline Le Faouder, Kyoichi Kodama, Junko Kyozuka, Erika Sallet, Guillaume Bécard, Marta Rodriguez-Franco, Thomas Ott, Justine Bertrand-Michel, Giles E D Oldroyd, Péter Szövényi, Marcel Bucher, Pierre-Marc Delaux Science (New York, N.Y.) 2021-05-21 pmid:34016782 doi:10.1126/science.abg0929

Publisher Correction: The calcium-permeable channel OSCA1.3 regulates plant stomatal immunity
Kathrin Thor, Shushu Jiang, Erwan Michard, Jeoffrey George, Sönke Scherzer, Shouguang Huang, Julian Dindas, Paul Derbyshire, Nuno Leitão, Thomas A DeFalco, Philipp Köster, Kerri Hunter, Sachie Kimura, Julien Gronnier, Lena Stransfeld, Yasuhiro Kadota, Christoph A Bücherl, Myriam Charpentier, Michael Wrzaczek, Daniel MacLean, Giles E D Oldroyd, Frank L H Menke, M Rob G Roelfsema, Rainer Hedrich, José Feijó, Cyril Zipfel Nature 2020-11-17 pmid:33199921 doi:10.1038/s41586-020-2954-9

The calcium-permeable channel OSCA1.3 regulates plant stomatal immunity
Kathrin Thor, Shushu Jiang, Erwan Michard, Jeoffrey George, Sönke Scherzer, Shouguang Huang, Julian Dindas, Paul Derbyshire, Nuno Leitão, Thomas A DeFalco, Philipp Köster, Kerri Hunter, Sachie Kimura, Julien Gronnier, Lena Stransfeld, Yasuhiro Kadota, Christoph A Bücherl, Myriam Charpentier, Michael Wrzaczek, Daniel MacLean, Giles E D Oldroyd, Frank L H Menke, M Rob G Roelfsema, Rainer Hedrich, José Feijó, Cyril Zipfel Nature 2020-08-27 pmid:32846426 pmc:PMC8435934 doi:10.1038/s41586-020-2702-1

Ligand-recognizing motifs in plant LysM receptors are major determinants of specificity
Zoltan Bozsoki, Kira Gysel, Simon B Hansen, Damiano Lironi, Christina Krönauer, Feng Feng, Noor de Jong, Maria Vinther, Manoj Kamble, Mikkel B Thygesen, Ebbe Engholm, Christian Kofoed, Sébastien Fort, John T Sullivan, Clive W Ronson, Knud J Jensen, Mickaël Blaise, Giles Oldroyd, Jens Stougaard, Kasper R Andersen, Simona Radutoiu Science (New York, N.Y.) 2020-08-09 pmid:32764065 doi:10.1126/science.abb3377

The negative regulator SMAX1 controls mycorrhizal symbiosis and strigolactone biosynthesis in rice
Jeongmin Choi, Tak Lee, Jungnam Cho, Emily K Servante, Boas Pucker, William Summers, Sarah Bowden, Mehran Rahimi, Kyungsook An, Gynheung An, Harro J Bouwmeester, Emma J Wallington, Giles Oldroyd, Uta Paszkowski Nature communications 2020-05-02 pmid:32355217 pmc:PMC7193599 doi:10.1038/s41467-020-16021-1

A plant's diet, surviving in a variable nutrient environment
Giles E D Oldroyd, Ottoline Leyser Science (New York, N.Y.) 2020-04-04 pmid:32241923 doi:10.1126/science.aba0196

An ancestral signalling pathway is conserved in intracellular symbioses-forming plant lineages
Guru V Radhakrishnan, Jean Keller, Melanie K Rich, Tatiana Vernié, Duchesse L Mbadinga Mbadinga, Nicolas Vigneron, Ludovic Cottret, Hélène San Clemente, Cyril Libourel, Jitender Cheema, Anna-Malin Linde, D Magnus Eklund, Shifeng Cheng, Gane K S Wong, Ulf Lagercrantz, Fay-Wei Li, Giles E D Oldroyd, Pierre-Marc Delaux Nature plants 2020-03-04 pmid:32123350 doi:10.1038/s41477-020-0613-7

Genetic strategies for improving crop yields
Julia Bailey-Serres, Jane E Parker, Elizabeth A Ainsworth, Giles E D Oldroyd, Julian I Schroeder Nature 2019-11-08 pmid:31695205 pmc:PMC7024682 doi:10.1038/s41586-019-1679-0

A combination of chitooligosaccharide and lipochitooligosaccharide recognition promotes arbuscular mycorrhizal associations in Medicago truncatula
Feng Feng, Jongho Sun, Guru V Radhakrishnan, Tak Lee, Zoltán Bozsóki, Sébastien Fort, Aleksander Gavrin, Kira Gysel, Mikkel B Thygesen, Kasper Røjkjær Andersen, Simona Radutoiu, Jens Stougaard, Giles E D Oldroyd Nature communications 2019-11-08 pmid:31695035 pmc:PMC6834629 doi:10.1038/s41467-019-12999-5

NODULE INCEPTION Recruits the Lateral Root Developmental Program for Symbiotic Nodule Organogenesis in Medicago truncatula
Katharina Schiessl, Jodi L S Lilley, Tak Lee, Ioannis Tamvakis, Wouter Kohlen, Paul C Bailey, Aaron Thomas, Jakub Luptak, Karunakaran Ramakrishnan, Matthew D Carpenter, Kirankumar S Mysore, Jiangqi Wen, Sebastian Ahnert, Veronica A Grieneisen, Giles E D Oldroyd Current biology : CB 2019-09-24 pmid:31543454 pmc:PMC6839406 doi:10.1016/j.cub.2019.09.005

Atypical Receptor Kinase RINRK1 Required for Rhizobial Infection But Not Nodule Development in Lotus japonicus
Xiaolin Li, Zhiqiong Zheng, Xiangxiao Kong, Ji Xu, Liping Qiu, Jongho Sun, Dugald Reid, Haojie Jin, Stig U Andersen, Giles E D Oldroyd, Jens Stougaard, J Allan Downie, Fang Xie Plant physiology 2019-08-15 pmid:31409696 pmc:PMC6776872 doi:10.1104/pp.19.00509

Engineering transkingdom signalling in plants to control gene expression in rhizosphere bacteria
Barney A Geddes, Ponraj Paramasivan, Amelie Joffrin, Amber L Thompson, Kirsten Christensen, Beatriz Jorrin, Paul Brett, Stuart J Conway, Giles E D Oldroyd, Philip S Poole Nature communications 2019-08-02 pmid:31366919 pmc:PMC6668481 doi:10.1038/s41467-019-10882-x

A protein complex required for polar growth of rhizobial infection threads
Cheng-Wu Liu, Andrew Breakspear, Nicola Stacey, Kim Findlay, Jin Nakashima, Karunakaran Ramakrishnan, Miaoxia Liu, Fang Xie, Gabriella Endre, Fernanda de Carvalho-Niebel, Giles E D Oldroyd, Michael K Udvardi, Joëlle Fournier, Jeremy D Murray Nature communications 2019-06-30 pmid:31253759 pmc:PMC6599036 doi:10.1038/s41467-019-10029-y

Characterizing standard genetic parts and establishing common principles for engineering legume and cereal roots
Doreen Feike, Andrey V Korolev, Eleni Soumpourou, Eiichi Murakami, Dugald Reid, Andrew Breakspear, Christian Rogers, Simona Radutoiu, Jens Stougaard, Wendy A Harwood, Giles E D Oldroyd, J Benjamin Miller Plant biotechnology journal 2019-04-26 pmid:31022324 pmc:PMC6835126 doi:10.1111/pbi.13135